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However, it is now clear that MRP1 serves a broader role than simply mediating the ATP-dependent efflux of drugs from cells

doi: 10.1016/j.biomaterials.2017.06.035 [DOI] [PubMed] [Google Scholar] 212.Xu JT, Shi RP, Chen GY, et al

Method Optimisation Varying amounts of O-pthaldialdehyde (OPA) reagent (110%, v / v ) (Sigma-Aldrich, Poole, UK) were titrated with 2 mM GSH to determine the optimal reactivity (product yield)

The freeze-drying process removes water, and without water, the chemical reactions that break down peptide bonds essentially stop

In addition, the further study on other animal models for PD and the careful evaluation of possible toxicity of our formulation might be warranted to verify its neuroprotective efficacy and safety before its clinical translation