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also found that mucus hypersecretion and muc5AC mRNA were significantly decreased when enzyme-degradation resistant VIP was delivered to the airways of mice with experimentally induced asthma [117]

ACS Pharmacol Transl Sci 3:749758
P.BhnerM.et al (2010)

This novel strategy successfully extended the duration of action, consequently reducing the early stages of obesity, diabetes mellitus, and fatty liver disease in mice that are caused by genetic mutations and dietinduced metabolic dysfunction without generating any tissue toxicity
