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The term costo refers to the ribs, chondro refers to cartilage, and itis refers to inflammation

10.1186/s12915-014-0056-6 BMC Biol

The tight junction protein occludin and the adherens junction protein alpha-catenin share a common interaction mechanism with ZO-1

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If the 4 mg maintenance arm proves non-inferior for weight maintenance in Phase 3, researchers may be able to titrate up to a high working dose during the active weight-loss phase, then step back down to a lower 4 mg maintenance dose for the long stabilization phase