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This process supports the regenerative capacity of organs including the liver, kidney, and muscle tissue making FOXO4-DRI a compelling candidate in research addressing age-related organ decline and chemotherapy side effects

65 , 68 , 69 Thus, iron deficiency may subsequently lead to reduced bone structure

doi: 10.1124/jpet.108.149211

In addition, we consider the role of functional polymorphisms in the human GPX1 gene on GPx1 expression and activity, and provide an update on the potential relationship between these polymorphisms and disease risk