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Description
Severity of B12 deficiency : If a confirmed B12 deficiency is present, some doctors will give daily injections to correct the deficiency before switching to a more infrequent maintenance dose

The biology is interesting enough that ongoing research is warranted, and I'm watching the human trial literature carefully

What Research Shows A 20192020 study in Orlando: BPC-157 alone 91.6% reported major knee pain relief BPC-157 + TB-4 75% experienced significant improvement Overall success rate 87.5% reported meaningful pain reduction Animal studies also show BPC-157 preserved cartilage, improved mobility, and prevented joint damage in osteoarthritis models

Although it is unclear how EGFR activation modulates GPx-1 activity, the increase in activity was rapid and peaked within 15 min, suggesting an event that required activation of existing GPx-1, possibly by phosphorylation or through alterations in proteinprotein interactions

The compound was first characterised and studied by Predrag Sikiri and colleagues at the University of Zagreb beginning in the 1990s
