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[DOI] [PubMed] [Google Scholar] 45.Tansey MG, Wallings RL, Houser MC, Herrick MK, Keating CE, Joers V

Although conjugating DFO to polymers has prolonged drug circulation, safe and effective chelating materials for chelation therapy should also possess features capable of regulating iron chelation levels to avoid removing too much iron too fast from cells, oxidation-induced degradable properties suitable for eliminating iron-bound chelates from the body and an overall lower drug cytotoxicity profile

However, its use is being explored as a potential treatment for a range of conditions including obesity, insulin resistance, metabolic syndrome, non-alcoholic fatty liver disease, fibromyalgia, ulcerative colitis, Crohns disease, functional constipation, IBS, and even cancer [153156]

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