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One of the main causes is oxidative stress, where highly reactive chemicals called reactive oxygen species (ROS) produced as a by-product of energy generation in mitochondria get out of control and start reacting with important cellular components like DNA, membranes, and protein

[DOI] [PubMed] [Google Scholar] 65.Mohn AR, Gainetdinov RR, Caron MG, Koller BH

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