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The naming inconsistency has created confusion, but the underlying compound remains identical regardless of which label a particular clinic or researcher uses

In addition, it has been reported that the downregulation of the glycolytic enzyme PGK-1 promotes the accumulation of 1,3-BPG, and is sufficient to generate glycerate-adducts, even if PARK7 is fully functional (Heremans et al., 2022)

This may be characteristic of vascularized drusen 25 , and OCTA would help in distinguishing between them

Since PBMCs can be obtained through minimally invasive methods, this characteristic has garnered clinical interest in investigating their potential to differentiate between stages of MASLD

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