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In a clinical study on epilepsy patients with implanted cervical VNS devices, active stimulation acutely raised resting metabolic rate and glucose uptake in BAT, with a strong correlation between increased energy expenditure and BAT activity (Vijgen et al
doi: 10.1002/glia.20967

GHK-Cu is often discussed for its ability to bind copper and deliver it in a form that the skin can recognize
