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Description
Glutamate, the main excitatory neurotransmitter, is tightly regulated through synthesis, transporters, and GABA balance, with genetic variants influencing risk for migraines, OCD, seizures, and schizophrenia.

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5-Amino-1MQ is a small molecule NNMT inhibitor investigated in preclinical models of nicotinamide metabolism and NAD+ salvage pathway signaling

Toxicity is not only a function of damage mechanisms, but is also determined by cellular resilience factors

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