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However, the import of glutathione into the nucleus under normal physiological conditions occurs at the expense of the cytosolic pool 85 which together with AITC generates an extreme demand for glutathione

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The injection can be repeated, but most surgeons limit injections to two or three per wrist before recommending surgery

Liu W, Chen Y, Golan MA, Annunziata ML, Du J, Dougherty U, et al

Mitochondrial uptake of calcium ions and the regulation of cell function