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Intracellular degrading enzymes ChaC1 and ChaC2 play a key role in downregulating intracellular GSH levels, exerting a counteractive effect to regulate intracellular GSH homeostasis

canettii C59 was achieved using the BAC-recombineering (BAC-rec) strategy 53

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Moreover, we showed that antagonism with some common chemotherapeutics makes inclusion of GPX4 inhibitors in conventional treatment protocols challenging, because some chemotherapeutic agents can interfere with ferroptosis

TABLE 1 Describes the effect of antidiabetic drugs on the action of ROS
