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Left ventricular cardiac function was measured in all patients pre-operatively at baseline before the administration of L-carnitine or placebo and 12 h post-operatively using conventional echocardiography to assess left ventricular ejection fraction (LVEF) and two-dimensional speckle tracking echocardiography (2D-STE) to determine left ventricular global longitudinal strain (2D-LV GLS)

In the field of cardiovascular diseases, PAG activates adrenergic receptors, promoting high platelet reactivity and inflammatory responses, notably increasing the risks of complications such as myocardial infarction, stroke and heart failure (9598)

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At that time, physicians were often reluctant to diagnose this multifaceted clinical syndrome as long COVID because routine diagnostics of blood samples or imaging in survivors of mild acute COVID-19 rarely yielded any pathological results [120]