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Description
Comparative genomics of DtxR family regulons for metal homeostasis in Archaea

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rather, it arises from a complex interplay of regulated transcriptional programs, epigenetic states, and environmental context, many of which remain modifiable
In a mouse oligodendrocytic cell model of ALD, NAC was able to prevent the increase in mitochondrial superoxide, depletion of mitochondrial GSH, and impairment in mitochondrial inner membrane potential caused by VLCFA [114]

These matrix changes may render the degenerated IVD as a more brittle stiffer tissue with less dynamic compliancy properties under load and more prone to the development of fissures in the IVD, further compromising its normal biomechanical functions (Vergroesen et al., 2015)