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Acetyl-L-carnitine shows neuroprotective and neurotrophic activity in primary culture of rat embryo motoneurons

Current evidence, including magnetic resonance imaging studies, suggests that skeletal muscle alterations resulting from GLP-1 RA-induced weight loss, such as enhanced insulin sensitivity and reduced muscle fat infiltration, are adaptive, thereby improving muscle quality despite concurrent reductions in lean mass [112]

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Controlledrelease technologies utilizing polymeric matrices, liposomes, or thermosensitive hydrogels further enhance local retention time, enabling prolonged therapeutic exposure without repeated clinical applications

Four-week pretreatment with LA and/or ALC prevented rotenone-induced accumulation of -synuclein and ubiquitin PD is marked by the accumulation of -synuclein- and ubiquitin-positive cytoplasmic inclusions known as Lewy bodies