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Role of the Alpha Toxin and Perfringolysin O in: Cytotoxicity Towards Macrophages and the Ability to Escape From Phagosomes of Macrophages PFO was discovered to have an essential part in both cytotoxicity and escape of macrophages, therefore making it a crucial virulence factor of gas gangrene, helping the bacterium resist being killed by macrophages

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Munirah MP, Norhayati MN, Noraini M