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[PubMed: 19567534] 55

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12 However, the lack of a control groups in both of these studies and combination topical cream containing other active ingredients makes it impossible to attribute these benefits solely to glutathione's antioxidant effect alone

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Targeting key antioxidant components in the Trx and Grx systems can induce genome instability

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333,334 Other targets of signaling pathways Dasatinib, a common drug for targeting SnCs, is a second-generation tyrosine kinase inhibitor that can downregulate the expression of senescence-associated biomarkers, including -galactosidase, p16, and p21

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