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At the molecular level, MT-1 seemed to reduce the mRNA expression of transforming growth factor 1 (TGF-1), collagen 1, tumor necrosis factor- (TNF-), intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1 (VCAM-1)

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Neurology 2006;66:1721-1726

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