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Description
Other than the BOLT primary analysis, no published studies or case reports describe an association between SCC and sonidegib treatment
Types of surgeries to improve or resolve nerve pain include release, repair, or removal

Affecting approximately 50% of patients with diabetes, DN is predominantly characterized by distal symmetric polyneuropathy, leading to sensory loss, pain, and motor dysfunction, often resulting in diabetic foot ulcers and lower-limb amputations

409,410 This holds promise for developing novel therapeutic strategies targeting the gut microbiota to manage DPN effectively

Epistatic and functional interactions of catechol-o-methyltransferase (COMT) and AKT1 on neuregulin1-ErbB signaling in cell models