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Rizo-Tllez SA, Sekheri M, Filep JG
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The primer sequences are described below: qPCR conditions were as follows (Table 1): Statistical analysis All graphs were generated using Graph Pad Prism 5
P21 increased new neurons in the dentate gyrus by 80%
The pH-sensitive characteristics of ionizable lipids confer endosomal escape activity to the LNPs, while the neutral surface of the LNPs in the physiological environment is beneficial for avoiding unspecific electrostatic interactions with biomaterials (Sun and Lu 2023)
