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In neurodegenerative diseases, the chronic oxidative stress environment exacerbates the vulnerability of neurons to apoptosis [230, 231]

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C th s dng hng ngy
October 59 1986

Enzyme purification experiments showed that Gdh1p and Gdh3p are hexamers (a6 50 kDa oligomeric structure) with the in vivo total NADP-GDH pool being a quite dynamic mixture of Gdh1p and Gdh3p monomers [15]