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A phase II study of clinical activity of SCH 717454 (robatumumab) in patients with relapsed osteosarcoma and Ewing sarcoma

I.|Berk, M

In normal cells, P-glycoprotein, MRP1, ABCG2, and several other clinically relevant MRP-related drug transporters are often expressed in a polarized manner and contribute to drug absorption (bioavailability), distribution (limiting drug access to so-called pharmacological sanctuaries such as the brain, cerebral spinal fluid, and testes), and elimination (efflux into bile or urine) (Fig

Bridging the Gap: Expanding Access to Minimally Invasive Thoracic Surgery to Reduce Health Disparities

Deng H, Yue JK, Zusman BE, Nwachuku EL, Abou-Al-Shaar H, Upadhyayula PS, et al
