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Mechanism: Glutathione inhibits tyrosinase, a key enzyme in melanin production, and promotes the synthesis of pheomelanin (a red/yellow pigment) over eumelanin (a black/brown pigment)
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On the other hand, a more recent study from 2015 found that beta-arbutin is more effective both on mouse melanoma cells and on human melanoma cells (btw, kojic acid was the most effective on human melanoma cells)
