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A Phase I Dose-Escalation Study OF PRI-724, A CBP/B-Catenin Modulator In Patients With Advanced Acute Myeloid Leukemia (AML)
elegans 2.1

Appendix 4

PMCID: PMC5572812

Regarding iron metabolism, NRF2 induces expression of FTH1 and heme oxygenase-1, promoting iron storage and detoxification to limit the labile iron pool and reduce Fenton reactions (93)