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Systematic Reviews and Meta-Analysis Multiple systematic reviews and meta-analyses have evaluated the efficacy and safety of oral 600 mg/day ALA in treating DPN, showing significant improvements in neuropathic pain and NCV [110]
Unfortunately, oxidative stress resulting from an imbalance between oxidative and antioxidant effects could lead to a variety of negative outcomes (Jones, 2024)

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Bibliographies were also reviewed to locate additional relevant articles
10.15252/msb.202211462 123 PoredosP.PoredosA
