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Methods: Authors used a computer-based gene profiling tool, The Connectivity Map, to identify a number of human genes regulated by GHK, relevant to regulation of cell differentiation, apoptosis and stem cell function

In experiments, scientists have shown that mice unable to generate glutathione die before birth

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Contrary to previous predictions, the increase of intracellular cysteine did not affect the cellular GSH pool, but concomitantly boosted extracellular cysteine concentrations

This is important because tissue GSH lowering is commonly noted in the context of several diseases as well as in aging