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Zakon, H
doi: 10.1167/iovs.18-26344 172 OmriS.OmriB.SavoldelliM.JonetL.Thillaye-GoldenbergB.ThuretG.et al
32 In the liver, ATP7B mobilizes Cu in secretory vesicles to the bile in order to prevent the accumulation of Cu
S 43 then carries out a nucleophilic attack on S 48 , leading to the formation of the redox-active disulfide bridge between Cys 43 and Cys 48 , followed by the cleavage of the covalent bond between S 48 and flavin atom C-4a, producing the reduced FADH anion with a negative charge on atom N-1
