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The underlying cause of this disorder is a polymorphism in the promoter region of the UGT isoform 1A1 gene ( UGT1A1*28 ) that increases the length of the promoter [97]
[DOI] [PMC free article] [PubMed] [Google Scholar] 434.Capone C, Cognat E, Ghezali L, Baron-Menguy C, Aubin D, Mesnard L, Sthr H, Domenga-Denier V, Nelson MT, Joutel A
Finding biomarkers may help create diagnostic tests that can be performed as soon as symptoms start to show up
Nov 2015;70(11):765-9
Unlike immunosuppressive drugs, TB-500 modulates rather than eliminates inflammatory responses
