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Hardiman O, Van Den Berg LH, Kiernan MC (2011) Clinical diagnosis and management of amyotrophic lateral sclerosis

Group B vitamins protect murine cerebellar granule cells from glutamate/NMDA toxicity

The hypothesis that GSSG functions as the oxidant for class III peroxidases during ROS production in apoplast, however, is not consistent with previous observations that a GSH peak was not observed in a bean apoplastic fluid before and after an oxidative burst and glutathione was less effective for the production of reactive oxygen species than free cysteine in an in vitro assay 37,38

If the treatment is inadequate due to poor understanding of B12 metabolism, and symptoms return as a result, that's due to poor research/lack of adequate knowledge on how to treat B12 deficiency properly in PA

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