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Typically, afflicted individuals have a history of mild to moderate acne before experiencing a sudden onset of severe, hemorrhagic, ulcerative lesions affecting the back, chest, and face, accompanied by fever, elevated white blood cell count, anemia, hepatosplenomegaly, myalgia, and arthralgia ( It is crucial to distinguish AF from acne conglobata and acne vulgaris

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10.3109/02713688109001822 139 RuanW.YuanX.EltzschigH

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Intramuscular Whether given intramuscularly (IM) or subcutaneously (SQ), the goal of B12 injections is to bypass the digestive system when stomach absorption of B12 is impaired

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Glutathione-responsive nanosystems are engineered to remain stable in circulation but undergo structural changes or drug release specifically in high-GSH tumor cells, improving therapeutic precision and reducing off-target toxicity

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doi: 10.1007/s00296-017-3718-1

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