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This relationship raises an intriguing question: does glutathione cleanse the kidneys
The investigation of 25 curcumin analogs surprisingly showed that dihydroxylated curcumin, monohydroxylated demethoxycurcumin, and mono- and di-hydroxylated bisdemethoxycurcumin, increased NEP activity, but curcumin did not

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The intake of pain-relieving drugs increased in the placebo group by 3.8 pills per patient per month and was reduced in the Pycnogenol group by 15 pills per patient per month at the end of the study

They kind of hit a bunch of articles and give you an update on what they found, but very general, very vague