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Conversely, exercise promotes neurogenesis, enhances synaptic plasticity, improves cognitive function, and reduces neurological disease incidence, making it a key intervention for treating central nervous system disorders and mitigating aging effects (Chow et al., 2022)

They proposed that NOX2 and NOX4 play a crucial role in the development of IIM, possibly by depleting NADPH to generate excessive ROS, leading to oxidative damage to tissue cells and inducing ferroptosis

doi: 10.1186/s12916-016-0742-z

Chronic inflammation and overtraining increase cortisol

Harkins, commander of the Military Assistance Command, Vietnam (MACV), made a much more optimistic assessment of the battle