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5-amino-1MQ is not FDA-approved for any indication

Catherine Sampson, Sierra Miller, Kehinde Ogunseye, and Erika Main for help with technical aspects of this study, Dr

Its chemical name is 5-Amino-1-methylquinolinium , and it functions as a targeted enzyme inhibitor rather than a signaling peptide

Mice in the vehicle cohort received three subcutaneous (SC) saline (1 ml/kg) injections/day (~0930, 1330, 1730 h) and mice in the treatment cohort received three SC injections of the NNMT inhibitor 5-amino-1MQ at a dose of 20 mg/kg/injection for a total dose of ~34 mg/kg/day of the parent compound (calculated according to free weight) for 11 days
