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In CRC, YTHDF3 is notably overexpressed and has been linked to poorer patient survival outcomes

Kidney Int 2002;62:914921

Hence, in the current study the direct effect of NAC on endothelial cells can't be ruled out and needs further investigation

As far as beneficial effects of NAC are concerned, the modulation of GLT-1 seems to be crucial for diminishing the excitatory glutamatergic transmission observed after drugs of abuse

Mouse strain differences in ozone dosimetry and body temperature changes. American Journal of Physiology-Lung Cellular and Molecular Physiology 272.1 (1997): L73-L77
