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Description
Intrinsic Factor replacement therapy can cause side effects such as: Pain or swelling at the injection site Allergic reactions to the synthetic intrinsic factor The adverse effects may be transient in some situations and get better with time, but they may also be severe in other circumstances and need medical treatment

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The liver can store the vitamin for a long time, so it may take a few years for deficiency and symptoms to develop

1977;11(1):1619 [DOI] [PMC free article] [PubMed] [Google Scholar] 8
