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Deterioration of CD was classified according to the CD activity index (CDAI) (34), which is a composite scoring system based on selected clinical symptoms, such as the number of liquid stools, the severity of abdominal pain, general well-being, extraintestinal CD manifestations, abdominal mass, use of antidiarrheal drugs, as well as haematocrit and body weight

J Clin Invest (2007) 117(11):34216

doi: 10.1155/2019/6175804 38 SametJMWagesPA

2019;5:e323
Moreover, the distances between the intra-domain probes were comparatively less affected (Supplementary Fig
