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This Questions and Answers document introduces the concept of a double negative nonclinical scenario (negative hERG assay and negative in vivo QTc Study) to demonstrate that a drug does not produce a clinically relevant QT liability

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We use the model to study the extent of liver damage caused by overdoses or by chronic use of therapeutic doses, and the effects of polymorphisms in glucoronidation enzymes

Celebrate Mom, a mother figure, someone special, or yourself with a gift that feels personal and well considered
