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Description
While the exact causative mechanism isnt always clear, high dose opioid use can lead to rhabdomyolysis, which can increase the risk of acute renal failure and death

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Mechanistically, the triple-agonist design is a deliberate departure from the GLP-1-monoagonist (liraglutide, semaglutide) and GIP/GLP-1-dual-agonist (tirzepatide) classes

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