glutathione s transferase antioxidant transferases: substrates, inihibitors and pro-drugs in cancer and neurodegenerative diseases Antioxidant function of glutathione. GST:

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Studies indicate that the FSP1-CoQ10 pathway can mitigate the impacts of ferroptosis inducers like erastin and RSL3 by decreasing ROS and lipid peroxide levels, thereby safeguarding cells from death.For instance, a recent investigation revealed that cells deficient in FSP1 exhibited markedly lower CoQ10 levels, coupled with significantly elevated lipid peroxides and ROS, underscoring the essential function of FSP1 in modulating CoQ10 and inhibiting ferroptosis (Lv et al., 2023b)

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As an alternative to vitrectomy, some ophthalmologists turned to a risky and somewhat controversial treatment: laser vitreolysis