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Oxidative stress, along with structural changes such as axonal loss and demyelination from toxic insults like hyperglycemia and alcohol consumption, are also associated factors

Enzymes that play a crucial role in protecting cells against ROS include glutathione peroxidase, which facilitates the reduction of hydrogen peroxide and organic peroxides, superoxide dismutase (SOD), which helps in the conversion of superoxide radicals into hydrogen peroxide, and catalase (CAT), which helps in maintaining optimal levels of hydrogen peroxide within cells by neutralizing it

At one point, bison were even on their way to extinction

(A) Control group, (B) LC group, (C) Diabetic group, (D) Diabetic+LC 50, (E) Diabetic+LC 100, (F) Diabetic+LC 200 (Tunnel staining, 400)

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