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Whilst, those belonging to CNS ECs for the delivery of nutrients into the CNS parenchyma include slc2a1GLUT1 required for transportation of glucose, slc7a1 for transport of cationic amino acids, slc16a1 and l-DOPA for supplying lactate and pyruvate and slc7a5 for the purpose of transporting neutral amino acids [6, 16]

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lack of NO release in vitro) and Larginine (i.e., hypotension