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This idea posits that excessive dopaminergic activity in the course of mania precipitates dopamine receptor down-regulation, which subsequently triggers a transition into a depressed state (245)

doi: 10.2174/0115680096343056240828190900 303 ShastryMJacobSRugoHSHamiltonE

They did not repair anything

[DOI] [PMC free article] [PubMed] 213.Xu Y, Ku B, Cui L, Li X, Barish PA, Foster TC, et al
