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Furthermore, when using cholesterol hydroperoxide (ChOOH, a specific GPX4 substrate) as a stressor, compound 102 could activate GPX4 in intact cells and protect them from ChOOH toxic effects ( Supplementary Figure S12B )
Nevertheless, the direct mechanism of MSCs targeting cuproptosis is novel and needs further exploration since cuproptosis may be implicated in the pathogenesis of IBD
doi: 10.3390/ijms22041671 7
Ascorbic Acid Ascorbic acid, or better known as Vitamin C, is an essential nutrient that your body needs to form cartilage, blood vessels, muscle and collagen in bones
Nature 419 , 925929 (2002)
