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Among the transgenic cohorts, those treated with intranasal GHK-Cu had significantly fewer detectable plaques in comparison to those receiving intranasal saline

Autophagy is also closely associated with cytoskeletal changes

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Ghrelin and leptin serve as primary hormones that manage hunger control mechanisms

Collectively, these findings position CAFs not merely as passive bystanders but as active sentinels of redox balance, functioning through lipid transfer, antioxidant donation, and transcriptional reprogramming to maintain a ferroptosis-resistant niche