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In addition, haem oxygenase 1 (HMOX1) is upregulated in embryonic ferroptosis, and inhibition of HMOX1 can maintain normal mitochondrial function, thereby preventing ferroptosis from occurring [16]

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Owing to the absence of -12 and -15 desaturase enzymes, which are necessary for forming carbon-carbon double bonds outside the -12 and -15 carbons, these precursors cannot be produced de novo ( Figure 1 ) in livestock, such as chickens, hence, they should be supplemented in the diet (Ngcobo et al., 2021)

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Accessed January 14, 2025