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Subgroup analyses were performed based on location (anterior vs posterior circulation), core size (large vs small core), treatment window (8h vs up to 24h), and imaging selection method (CT-only vs perfusion imaging/MRI), using the Cochran Q-test Results: We collected data from 21 trials randomizing 5,673 patients

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Changes in FDA leadership, congressional oversight, or executive branch priorities could influence enforcement approaches and regulatory interpretations

Adverse events

Reconstitution is a simple process, but proper procedure must be followed to avoid degrading the peptide and to achieve accurate, sterile dosing