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doi: 10.1016/j.heliyon.2023.e22973
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Horvat et al

When NRX is oxidized by NADPH oxidase 1 (NOX1)-derived H2O2 or lipid peroxide (ROOH), DVL is released and inhibits glycogen synthesis kinase 3 (GSK3) in the -catenin degradation complex, thereby stabilizing the -catenin in the cytoplasm and partially entering the nucleus to activate the target gene GPX2 by correlation with the TCF/LEF transcription factor family (Kipp et al., 2012) (Figure 2)
Infused with powerful antioxidants like Glutathione, Vitamin C, and Niacinamide, this cream effectively reduces dark spots, evens out skin tone, and enhances overall radiance
