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Compared with placebo, pioglitazone significantly reduced the histologic feature scores, and a greater proportion of subjects in the pioglitazone group achieved resolution of MASH

Cell death LEC were trypsinized 48 h post transfection and incubated with 2 g/mL propidium iodide (PI) (P4170, Sigma)

Arrows indicate significant upregulation or downregulation, and no arrow sign in proteins with a fold change lower than 1.5 indicates no significant change

Immune Homeostasis An infectious agent triggers a pathological immune response orchestrated by the several types of immune cells along with secreted biomolecules