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These options, primarily including NMDA receptor antagonists and cannabinoids, often have more limited evidence, narrower mechanisms of action, or higher side effect burdens
It's more often seen in patients with chronic hepatitis or cirrhosis, resulting in bile stagnation
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[20] It can also be injected intravenously for the purpose of treating cyanide poisoning, as the hydroxyl group is displaced by cyanide, creating a non-toxic cyanocobalamin that is excreted in urine
