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The increased lactate in the prefrontal cortex affects histone lactylation, particularly histone H1

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Luo H, Liu H-Z, Zhang W-W, Matsuda M, Lv N, Chen G, et al

627 In a large observational study with 115,664 participants who were followed for 812 years, higher folate intake in particular was associated with lower risks of stroke, heart attack, and cardiovascular mortality

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